Immunolocalization of enzymes, binding proteins, and receptors sufficient for retinoic acid synthesis and signaling during the hair cycle

Helen B. Everts, PhD. Vanderbilt University Medical Center, Nashville, TN Vitamin A is essential for the development and maintenance of multiple epithelial tissues, including skin and hair (Frazier and Hu, 1931, Peck and DiGiovanna, 1994, Wolbach and Howe, 1925). The skin takes up circulating retinol and can either store it in the form of retinyl esters or metabolize it to retinoic acid (RA,…

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Exogen, The Shedding Phase Of The Hair Cycle (Jun 2005)

Exogen, the shedding phase of the hair cycle-Kurt Stenn, M.D.Director of Skin Biology Research CenterRW Johnson Pharmaceutical Research InstituteSkillman, NJ Hair serves the functions of camouflage, communication and protection from heat loss, trauma, infestation and sunlight. Inherent in hair growth is the ability to shed, thus cleansing the skin surface of adherent insects, bacteria, fungi…

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NAHRS Poster Prizes for 2005

Poster Prizes: Dr. T. Schlake, Freiburg, Germany. “Multiple roles of IGF-1 and IGFBPs in the hair follicle” Dr. M. Ito, University of Pennsylvania, Philadelphia. “Bulge cells are necessary for hair follicle survival but not epidermal homeostasis”. Dr. Mark Hutchin, University of Michigan, Ann Arbor. “Hedgehog signal transduction in hair follicle epithelium is essential for proper…

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How Close Are We to Solving the Puzzle? (2004)

How Close Are We to Solving the Puzzle? Review of the Alopecia Areata Research Workshop -David Norris, M.D. University of Colorado Health Sciences Center Denver, CO Speakers at the Fourth Research Workshop on Alopecia Areata have clearly presented the state of current knowledge in three fundamental areas of research in alopecia areata : genetics, immunology, and…

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